Howard Y Chang Selected Research

Chromatin

1/2021	Chromatin accessibility associates with protein-RNA correlation in human cancer.
1/2021	LKB1 inactivation modulates chromatin accessibility to drive metastatic progression.
12/2020	Author Correction: Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis.
11/2020	Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis.
1/2020	Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity.
1/2020	Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia.
12/2019	Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia.
11/2019	Circular ecDNA promotes accessible chromatin and high oncogene expression.
1/2019	Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion.
10/2018	The chromatin accessibility landscape of primary human cancers.

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Howard Y Chang Research Topics

Disease

57	Neoplasms (Cancer) 12/2022 - 08/2005
11	Breast Neoplasms (Breast Cancer) 01/2016 - 01/2006
9	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2006
5	Fibrosis (Cirrhosis) 09/2021 - 02/2009
5	Wounds and Injuries (Trauma) 09/2021 - 01/2006
5	Systemic Scleroderma (Systemic Sclerosis) 12/2020 - 02/2009
5	Leukemia 12/2019 - 02/2009
4	Infections 01/2021 - 07/2020
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2021 - 12/2015
3	Virus Diseases (Viral Diseases) 07/2020 - 06/2015
3	Carcinogenesis 01/2020 - 01/2009
3	Hypoxia (Hypoxemia) 01/2020 - 01/2006
2	Neuroblastoma 10/2022 - 01/2020
2	COVID-19 10/2020 - 07/2020
2	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 02/2009
2	Atopic Dermatitis (Atopic Eczema) 07/2017 - 01/2008
2	Inflammation (Inflammations) 06/2016 - 07/2013
2	Carcinoma (Carcinomatosis) 01/2016 - 06/2007
2	Skin Diseases (Skin Disease) 01/2013 - 08/2003
2	Retinoblastoma (Glioblastoma, Retinal) 11/2010 - 02/2010
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 02/2008 - 07/2006
2	Pain (Aches) 02/2008 - 07/2006
1	Neuromuscular Diseases (Neuromuscular Disease) 01/2022
1	Colorectal Neoplasms (Colorectal Cancer) 12/2021
1	Cicatrix (Scar) 09/2021
1	Thyroid Neoplasms (Thyroid Cancer) 01/2021
1	Adenocarcinoma of Lung 01/2021
1	Lung Neoplasms (Lung Cancer) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2020
1	Bites and Stings (Sting) 10/2020
1	Brain Edema (Cerebral Edema) 10/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2020
1	Intellectual Disability (Idiocy) 10/2019
1	Autistic Disorder (Autism) 10/2019
1	Autism Spectrum Disorder 10/2019
1	Neurodevelopmental Disorders 10/2019
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2019
1	Basal Cell Carcinoma (Rodent Ulcer) 01/2019
1	X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation 01/2019
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2019
1	Mandibulofacial Dysostosis (Treacher Collins Syndrome) 01/2018
1	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 10/2017
1	Lymphoma (Lymphomas) 10/2017
1	Eczema 07/2017

Drug/Important Bio-Agent (IBA)

24	ChromatinIBA 01/2021 - 06/2007
17	Proteins (Proteins, Gene)FDA Link 10/2022 - 01/2008
14	Long Noncoding RNAIBA 01/2020 - 04/2010
9	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2012
8	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 04/2016
7	Transcription Factors (Transcription Factor)IBA 12/2019 - 06/2007
6	Histones (Histone)IBA 01/2020 - 06/2007
5	Lysine (L-Lysine)FDA Link 01/2020 - 06/2007
4	Chimeric Antigen ReceptorsIBA 10/2022 - 10/2020
4	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2022 - 06/2011
3	Pharmaceutical PreparationsIBA 12/2022 - 01/2008
3	Estrogen ReceptorsIBA 01/2016 - 08/2012
3	Biological ProductsIBA 06/2009 - 06/2006
2	AntigensIBA 10/2022 - 10/2019
2	Phosphotransferases (Kinase)IBA 01/2021 - 02/2009
2	Immunoglobulin G (IgG)IBA 10/2020 - 07/2020
2	Immunoglobulin A (IgA)IBA 10/2020 - 07/2020
2	AntibodiesIBA 10/2020 - 07/2020
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2020 - 01/2019
2	MicroRNAs (MicroRNA)IBA 01/2020 - 01/2011
2	Circular RNAIBA 10/2019 - 07/2017
2	TransposasesIBA 10/2018 - 07/2015
2	RNA Helicases (RNA Helicase)IBA 05/2016 - 12/2015
2	Messenger RNA (mRNA)IBA 05/2016 - 01/2013
2	Biomarkers (Surrogate Marker)IBA 08/2012 - 07/2012
2	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 09/2011 - 10/2006
2	Polycomb Repressive Complex 2IBA 04/2010 - 06/2007
2	tegaserod (Zelnorm)FDA Link 02/2008 - 07/2006
1	GlypicansIBA 10/2022
1	oncofetal antigensIBA 10/2022
1	Oncogene Proteins (Oncogene Protein)IBA 10/2021
1	salvianolic acid BIBA 09/2021
1	CollagenIBA 09/2021
1	SOXF Transcription FactorsIBA 01/2021
1	Viral RNAIBA 10/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2020
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2020
1	Acetates (Acetic Acid Esters)FDA Link 01/2020
1	Small Cytoplasmic RNAIBA 01/2020
1	Pyruvic Acid (Pyruvate)IBA 01/2020
1	Differentiation AntigensIBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	Glycerol (Glycerine)FDA LinkGeneric 01/2020
1	alpha-hydroxyglutarateIBA 01/2020
1	AntioxidantsIBA 01/2020
1	CarbonIBA 01/2020
1	6-methyladenineIBA 10/2019
1	Lamin Type A (Lamin A)IBA 01/2019
1	Programmed Cell Death 1 ReceptorIBA 01/2019
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2018
1	Histone Deacetylase InhibitorsIBA 10/2017
1	dupilumabIBA 07/2017

Therapy/Procedure

19	Therapeutics 10/2022 - 08/2003
6	Immunotherapy 01/2021 - 01/2018
2	Drug Therapy (Chemotherapy) 01/2016 - 07/2012